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Genetics of Sexual Behavior
1. How does a male mouse react, when another male mouse is dropped into its cage?
Sniffs it to decide if it's a castrated male or not. Fights if the intruder is castrated, leaves it alone if not. Sniffs it to decide if it's a castrated male or not. Leaves it alone if the intruder is castrated, fights if not. Immediately starts mating! Tries to climb out of cage and run away.
2. The animals of which species secrete oxytocin and vasopressin?
Voles. Mice. Humans. All of the above.
3. How to make a female mouse bisexual?
Destroy its vomeronasal organ. Destroy its main olfactory epithelium. Inject it with oxytocin. Castrate it.
4. How to make a male prairie vole polygamous?
Prairie voles already are polygamous! Block vasopressin receptors. Feed it vasopressin. House it with multiple female voles.
5. How is human sexual identity linked to the size of certain brain areas?
Polygamous people have larger main olfactory epithelium than monogamous people. Female-to-male transsexuals have a certain brain area of the same size as men, but different than women. Homosexual men have a smaller vomeronasal organ than heterosexual men. There is no brain area whose size would be correlated with sexual identity.
6. What would happen to a male mouse if we removed its main olfactory epithelium?
Would start fighting with females instead of mating. Would start mating with females and males. Would start mating with males, and fighting with females. Wouldn't mate with females and fight with other males anymore.
7. The smell of which people I would find the most attractive?
The ones with the most similar MHC. The ones with partially different MHC. The ones with the most similar TRP channels. The ones with partially different TRP channels.
8. How does oxytocin make female voles - and women! - more attached to their partners?
It blocks the memories of all previous partners. It makes them infertile to all other partners. It helps to link the pleasant sensation with the features of the partner (what he looks, sounds, smells like). It makes them bisexual.
9. What is the definition of a mouse pheromone?
A molecule that regulates mouse immunity to pathogens (invading bacteria, viruses, etc) A chemical compound, secreted by mice, that makes other mice lose their sense of smell. A receptor for hormone that is released during mating: specifically, oxytocin in females, vasopressin in males. A chemical compound, secreted by mice, that triggers a specific behavior in other mice.
10. How do we test whether a vole is monogamous or polygamous?
Knock out a gene in its main olfactory epithelium. Smell it! Monogamous voles have a distinct smell of oxytocin. Keep it in a cage alone, then put another vole of the same sex into the same cage, see what happens: if they mate or fight. Find out if it prefers to be with a vole that it has mated with, or with a new vole that it hasn't seen before.
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Genetics of Sexual Behavior